KinshipAssembly: comparación genética para flujos MPI/DVI
🧬 Introduction In humanitarian and forensic genetics, one of the most computationally tedious problems is also one of the most consequential: systematically comparing a set of reference family pedigrees against a set of candidate biological relatives to find which pairs are actually related to the same missing person. This is the core challenge of Missing Person Identification (MPI) and Disaster Victim Identification (DVI) workflows. A defining constraint in all these scenarios is that the person of interest is not always genotyped. They may be deceased and unidentified, disappeared, suspected of theft and identity swap, or simply unwilling to provide a biological sample — or their remains may have been cremated or commingled in an ossuary, making individual sampling no longer possible. The analysis must therefore rely exclusively on the genotypes of their relatives — making indirect kinship inference the only available path to identification. ...




